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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 4
First page : ( 1197) Last page : ( 1203)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00215.3

Underlining some important aspects behind the role of enzyme immobilization in pharmaceutical technology

Kukreja Simran, Priya Sonal, Bhondekar Shraddha, Verma Nupur, Jain Sonal, Golchha Aivant, Sinha Ganesh, Kumar Shubham, Mandal Chandan, Patel Asha, Agrawal Mukta, Tripathi D. K.,  Ajazuddin, Alexander Amit*

Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, India, 490024

*Corresponding Author E-mail: itsmeamitalex@gmail.com

Online published on 17 July, 2017.

Abstract

The objective of this review article is to discuss the potential of sodium alginate as a biopolymer in the formulation development and its allied applications. There is a growing trend in pharmaceutical in food industry to avoid the harsh condition in the preparation for administration to the body or for the storage purpose as it induce the side effects, instability or loss of therapeutic effect of the medicament. The immobilization method is a versatile functional biomaterial for viscosity enhancement, stabilizer, matrixing agent, encapsulation polymer, bio adhesive and film former in transdermal and transmucosal drug delivery. Among various tested methods of this process that make use of different enzyme-carrier interactions, immobilization by adsorption on solid carriers has appeared most common. According to these findings, in this review we present a comparative analysis of the literature reports on the recent trends in the immobilization of the enzymes by adsorption. In this review article, the various aspects of pharmaceutical microemulsin where compile together and the target audience are specifically the M. Pharm and B. Pharm student so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

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Keywords

Immobilization, Adsorption, Cross linking, Microencapsulation.

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