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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 12
First page : ( 4439) Last page : ( 4441)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00817.4

Efficacy of Cox-2 inhibitors in the Clinical Management of TMJ Arthritis: A Review

Kumaresan Gayathri Devi1,*, Dhanraj M.2

1CRRI, Saveetha Dental College, Chennai

2Professor, Department of Prosthodontics, Saveetha Dental College, Chennai

*Corresponding Author E-mail: kgayathridevi11@gmail.com

Online published on 26 March, 2018.

Abstract

In the clinical management of arthritis, the choice of nonsteroidal anti-inflammatory drug (NSAID) remains confusing and controversial. The main objective of this review is to addresses the main arguments for the pharmacological and clinical use of COX-2 inhibitors for the clinical management of arthritis. This review concluded that, COX-2 inhibitors are effective and are associated with increased risk of GI, renal, and CV, adverse effects. Complete understanding of the patient's co-morbid conditions and concomitant medications, coupled with precise monitoring during the treatment, may help to decrease the threat of adverse effects induced by selective COX-2 inhibitors.

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Keywords

COX 2 inhibitors, NSAID, TMJ Arthritis.

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