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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 10
First page : ( 3301) Last page : ( 3304)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00585.6

Evaluation of Anti-inflammatory Activity of Different Extracts of Alpinia galanga

Das Renuka J.1,*, Duragkar N J1, Umekar Milind J.1, Katolkar Parimal2

1Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, 441002, Maharashtra

2Kamla Nehru College of Pharmacy, Butibori, Nagpur, 441108, Maharashtra

*Corresponding Author E-mail: parimal.katolkar@gmail.com

Online published on 26 March, 2018.

Abstract

Inflammation is the local response of living mammalian tissues to injury due to any agent. It is the body defense reaction in order to eliminate or limit the spread of injurious agent, followed by removal of the necrosed cells and tissues, but the sign and symptoms which are produced during healing process cannot tolerable. The present study was aimed to investigate the anti-inflammatory activity of different extracts of Alpinia galanga in wistar albino rats. In this study, both acute and sub-acute inflammation models were used to evaluate the antiinflammatory activity of Alpinia galanga. In acute model, carrageenan was used to induce inflammation in rat hind paw and in subacute inflammation, cotton pellets induced granuloma was performed. The extracts have significantly (p ≤ 0.05) decrease in paw edema volume and wet weight and dry weight of Cotton pellets as compared to the untreated vehicle control group.

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Keywords

Anti-inflammatory activity, Diclofenac sodium, Dexamethasone, Cotton pellet granuloma, Alpinia galanga..

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