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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 1
First page : ( 58) Last page : ( 60)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00014.2

In-Vitro Study of Anthelmintic Activity of Eclipta prostrata (L) y various Extracts

Kousalya M*, Geetha P, Jesuraja A, Kumar M Vinoth

Department of Pharmacology, School of Pharmaceutical sciences, Vels University (VISTAS), Chennai

*Corresponding Author E-mail: kouspharma@gmail.com

Online published on 29 April, 2017.

Abstract

Objective

the present study was conducted to validate in-vitro anthelmintic activity of various extract hexane, ethyl acetate, ethanol, water of eclipta prostrata (l)., aganist pheritima posthuma by petri-dish method.

Method

the in-vitro trial for anthelmintic activity of various extract of eclipta prostrata(l)., was conducted on mature live pheritima posthuma by petri-dish method. The extracts were used at the concentration of 5mg, 10mg, and 15mg and observation were made on their viability at room temperature.

Results

among the various extract, only ethyl acetate and ethanol have anthelmintic activity. 5mg, 10mg, 15 mg/ml of ethyl acetate have produced paralytic effect at 34 minutes minutes, 29 minutes and 20 minutes and mortality was confirmed at 111 minutes, 61 minutes and 46 minutes. 5mg, 10mg, 15 mg/ml of ethanol have produced paralytic effect at 27 minutes, 23 minutes and 17 minutes and mortality was confirmed at 83 minutes, 72 minutes and 34 minutes respectively.

Conclusion

An anthelmintic has been confirmed as the various extract shows good anthelmintic activity against pheritima posthuma. In the present investigation, the whole plant of eclipta prostrata (l)., was taken up for extensive studies “ preliminary phytochemical and pharmacological studies of the whole plant of eclipta prostrata (l)., (asteraceae).

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Keywords

Eclipta prostrata (L), anthelmintic, Pheritima posthuma, Albendazole, soxhlet extraction.

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