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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 1
First page : ( 18) Last page : ( 20)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00005.1

Clinical Assessment and Comparison of Lipid Profiles among Coronary Artery Disease and type 2 Diabetes Mellitus Patients receiving Statin Therapy

Kalaivanan S, Sarumathy S*, Ebens J Anisha, Kumar K Naresh, Parveen A Roobena, Ashraf M. Nasreen

Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University (VISTAS), Pallavaram, Chennai-600117, Tamilnadu, India

*Corresponding Author E-mail: saruprabakar@gmail.com

Online published on 29 April, 2017.

Abstract

Aim and Objective

The aim of study is to assess and compare the lipid profiles among diabetic and coronary artery disease (CAD) patients receiving statin therapy.

Methods

This retrospective observational study was carried out in a cardiac specialty hospital for a period of 6 months from January-June 2015. The inclusion criteria included adult patients greater than 18 years of age with the diagnosis of coronary artery disease or diabetes mellitus receiving statin therapy. CAD patients with any other co morbidity were excluded in the study. Lipid profile such as low-density lipoproteins (LDL), high-density lipoproteins (HDL), very-low-density lipoprotein (VLDL), total cholesterol (TC), triglycerides (TGL) were assessed.

Results

The overall prevalence of dyslipidemia in our CAD patients was greater. More number of male patients was affected with CAD and diabetes when compared to female patients. No significant changes were observed in HDL levels. The study concludes that the incidence and the lipid profile for both the study groups were found to be high. The lipid parameters were assessed and compared for both the study groups which showed statistically no significance difference. Aggressive therapy of diabetic dyslipidemia will probably reduce the risk of coronary heart diseases (CHD) in patients with diabetes. Lowering triglycerides and increasing HDL cholesterol with a fibrate is associated with a reduction in cardiovascular events in patients with clinical CHD, low HDL, and near-normal levels of LDL.

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Keywords

Coronary artery disease, Diabetes Mellitus, Cholesterol.

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