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Research Journal of Pharmacology and Pharmacodynamics
Year : 2017, Volume : 9, Issue : 3
First page : ( 122) Last page : ( 130)
Print ISSN : 0975-4407. Online ISSN : 2321-5836.
Article DOI : 10.5958/2321-5836.2017.00021.0

Antipsoriatic Activity of gel containing Methylsulphonylmethane Powder and seed oil of Pongamia pinnata Linn.

Ms. Balasaheb Salunke Pradnya1,*, Dr. Balvant Patil Sandeep2, Ms. Kadam A.T.1

1Assistant Professor, LNBC Institute of Pharmacy, Raigaon Satara, Maharashtra, India, 415020

2Associate Professor, Department of Pharmacology, Adarsh College of Pharmacy, Vita Dist Sangli

*Corresponding Author E-mail: pradnyasalunke89@gmail.com

Online published on 24 May, 2018.

Abstract

To develop gel using Methylsulphonylmethane powder and seed oil of Pongamia pinnata Linn. to minimize side effects of current therapy. All prepared formulations were evaluated for pH, Viscosity, spradability, Extrudability. The release of optimized batch was carried out using Cellophane membrane into Phosphate buffer 6.8 at 37°C. The Characterization was carried out by using FTIR, DSC, SEM analysis. In-vtro & In-vivo activities were performed by using HaCaT Cell line and Mouse tail model respectively

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Keywords

Psoriasis, Orthokeratosis, Pongamia pinnata, Methylsulphonylmethane.

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