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Research Journal of Pharmacology and Pharmacodynamics
Year : 2016, Volume : 8, Issue : 3
First page : ( 97) Last page : ( 105)
Print ISSN : 0975-4407. Online ISSN : 2321-5836.
Article DOI : 10.5958/2321-5836.2016.00018.5

Anti Diabetic activity and Toxicity Study of Petroleum Ether Extracts of Ixora coccinea Flower in Streptozotocin Induced Diabetic in Albino Rat Model

Johnson D. Benito*, Faisal N.V., Rashid K., Haleel Mohammed, Venkatanarayanan V.

Department Of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore

*Corresponding Author E-mail: benitopharma@gmail.com

Online published on 18 October, 2016.

Abstract

Diabetic millets1 often referred to simply as diabetes (Ancient Greek: diabetes” to pass through [urine]”) is a syndrome of disorder metabolism, usually due to a combination of hereditary and environment causes, resulting in abnormally high blood sugar level (hyperglycemia). Diabetes is described as starvation in the midst of plenty. Because the body will have high amount of glucose level but the cells are incapable of consume it because of osmotic difference Insulin is a hormone produced in the pancreas, which enable body cells to absorb glucose, to turn into energy. If the body cells cannot absorb the glucose, the glucose accumulates in the blood (hyperglycemia), leading to acute metabolic complications including keto acidosis and in the long term contribute to chronic micro-vascular complications.

Ixora coccinea is a low-growing tropical shrub notable for its bright coloured flowers which are composed of many small blooms massed together into dense, flat-topped flower heads. Ixora coccinea is one of the few Ixora species that make good indoor plants along with several kinds developed from it. It is primarily ornamental plant. Cut specimens are long lasting and are often used in floral arrangements. It is sometimes used as a hedge. In tropical Asia the flowers, bark and leaves of this plant are used in traditional medicine.

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Keywords

Ixora coccinea, Streptozotocin Induced Diabetic.

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