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Research Journal of Pharmacology and Pharmacodynamics
Year : 2015, Volume : 7, Issue : 4
First page : ( 181) Last page : ( 183)
Print ISSN : 0975-4407. Online ISSN : 2321-5836.
Article DOI : 10.5958/2321-5836.2015.00036.1

In-Vitro Anthelmintic Evaluation of Polyherbal Formulation: Krumighattini Tablet

Khan Shahin1, Meena Ajay Kumar2, Saluja Ajay1,*

1A. R. College of Pharmacy & G. H. Patel Institute of Pharmacy, Anand

2Central Council for Research in Ayurvedic Science, Janakpuri, New Delhi

*Corresponding Author E-mail: inshah01@rediffmail.com, ajaysheera@gmail.com

Online published on 8 December, 2015.

Abstract

Ayurveda has abundant collection of effective formulations against diseases. The polyherbal formulation contains Vernonia anthelmintica, Curcuma longa, Piper longum, Mallotus philippinensis, Operculina turpethum, Terminalia chebula, Butea monosperma, and Red ochre. The present study deals with anthelmintic evaluation of ayurvedic formulation. Various concentrations of polyherbal formulation (10 mg/ml, 20 mg/ml and 30 mg/ml) in 50 ml of normal saline were taken. The results were compared with standard albendazole (10mg/ml, 20mg/ml and 30 mg/ml) and control was taken as normal saline (0.9% NaCl). The results were expressed in terms of time in minutes for the paralysis and time of death of the worms. Paralysis and death time were analyzed using one way ANOVA analysis using Graph pad prism 2.01 Software. The study indicates that polyherbal formulation shows more potent anthelmintic activity than standard reference.

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Keywords

Polyherbal formulation, Krumighattini tablet, anthelmintic activity, albendazole.

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