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Research Journal of Pharmacology and Pharmacodynamics
Year : 2015, Volume : 7, Issue : 1
First page : ( 19) Last page : ( 22)
Print ISSN : 0975-4407. Online ISSN : 2321-5836.
Article DOI : 10.5958/2321-5836.2015.00004.X

Prescribing Trends of Antidiabetic Fixed dose combinations in a rural tertiary care teaching hospital in Central India: An Observational, cross-sectional study

Santra Diptendu*, Totade Sangita

J.N. Medical College, Sawangi (M), Wardha (Maharashtra)

*Corresponding Author E-mail: diptendusantra@gmail.com

Online published on 2 May, 2015.

Abstract

Objective

To assess prescribing trends of Fixed dose combination antidiabetics in Diabetes Mellitus patients.

Materials and Methods

An observational, cross-sectional study was carried out in the Medicine OPD of AVBRH, Sawangi(M), Wardha. A total of 500 Diabetes Mellitus Patients were selected for the study after fulfilling the inclusion/exclusion criteria.

Results

Out of 500 patients 484 patients were of type-II DM in whom 5 FDCs were prescribed. Maximum prescribed FDCs were of Metformin and sulfonylurea Metformin + Glimepiride (n=74) and Metformin + Glipizide (n=37). Following FDCs were Metformin + Voglibose (n=52), Glimepiride + Pioglitazone (n=18) and least prescribed was Metformin+ Glimepiride + Voglibose (n=10). All the drugs were prescribed by brand names. Total of 191 patients (39.46%) were prescribed Antidiabetic FDCs.

Conclusion

All Antidiabetic FDCs prescribed were rational. FDCs in Antidiabetics are useful in combination therapy for increasing patient compliance and achieving euglycemia more effectively.

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Keywords

Prescribing trends, Diabetes Mellitus, Fixed dose combinations.

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