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Research Journal of Pharmacology and Pharmacodynamics
Year : 2019, Volume : 11, Issue : 3
First page : ( 95) Last page : ( 100)
Print ISSN : 0975-4407. Online ISSN : 2321-5836.
Article DOI : 10.5958/2321-5836.2019.00017.X

Phytopharmacological Study of Areca catechu leaf

Patel Nishant. M.1,*, Suryawanshi H. P., Pawar S. P.

P.S.G.V.P. M'S College of Pharmacy, Shahada, (MS), India

*Corresponding Author E-mail: nishantpatel264@gmail.com

Online published on 31 December, 2019.

Abstract

Areca catechu (Arecaceae) is an erect unbranched palm tree, growing mainly in south and Southeast Asian countries. It is commonly used in day to day life. In present investigation an attempt has been made for the pharmacognostic standardization and phytochemical evaluation of Areca catechu leaves. The pharmacognostic evaluation comprises of detailed macroscopy, powdered microscopy, quantitative microscopy and physical constants such as ash and extractive values. The leaves extract were subjected to preliminary phytochemical screening. The data obtained in present study will serve as valuable tool for identification, authentication and detection of adulterants standardization and quality control of the drug. In this research work the anthelmintic property of leaves extract of Areca catechu belonging to family Arecaceae was studied for anthelmintic activity against Pheritima Posthuma (Indian earthworm). The leaves powder of Areca catechu was subjected to successive extraction by maceration using solvents like Acetone + Aqueous, Pet. Ether and Alcohol. Four concentrations (25, 50, 75 and 100 mg/ml) of different extract of leaves were studied in a bioassay, which involved the determination of time of paralysis and time of death of the worms. 100 mg/ml conc. of aqueous + acetone extract of leaves of Areca catechu reveal considerable anthelmintic activity as compared to other three conc. and piperazine citrate (10 mg/ml). Piperazine citrate and saline water were including in the assay as standard reference drug and control, respectively.

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Keywords

Areca catechu, Anthelmintic activity, Phytochemistry.

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