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Research Journal of Pharmacology and Pharmacodynamics
Year : 2018, Volume : 10, Issue : 4
First page : ( 163) Last page : ( 165)
Print ISSN : 0975-4407. Online ISSN : 2321-5836.
Article DOI : 10.5958/2321-5836.2018.00030.7

Pharmaceutical Evaluation of Nirgundi Ghanavati in Pureeshajakrimi

Dr. Jena Banashree1,*, Dr. Nanda G.C.2, Dr. Khuntia Bipin Bihari3

1Ph D Scholar, Department of Kayachikitsha, Gopabandhu Ayurveda Mahavidyalaya, Puri

2Asst. Director and Head, DR. Achint Laxmi Palti Research Center for Ayurveda VHS Campus, Chennai, India

3Professor and HOD, Kriyasharira, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha

*Corresponding Author E-mail: drbanashreejena@gmail.com

Online published on 27 December, 2018.


Ayurveda has taken the foremost place in the management of various diseases; one of them is Pureeshajakrimi roga which can be correlated with Helminthiasis or Intestinal worm infestation due to its clinical appearance. Helminthes are parasitic worms. They are most common infectious in humans in developing countries and produce a global burden of disease that exceeds better known conditions. Pureeshajakrimi or intestinal helminthiasis represents one of the most prevalent parasitic diseases. From the time immemorial, Krimi Roga is prevailing in this world. Its description is found in almost all ancient texts including Vedas. According to Ayurveda 4 types of Krimis[1] i.e. Pureeshaja, Raktaja, Kaphaja, Malajahave been described which is overall divided into 2 i.e. Bahya & Abhyantara. Nirgundi is described as Krimighna i.e. vermifuge (to kill the intestinal worms) as per Carak Samhita, Dhanwantari Nighantu and Kayadeva Nighantu and Bhavaprakash. In the present study Nirgundi Ghanavati is selected for taking orally as per Carak Samhita Sutrasthana 4/15[2, 3]. The present study was carried out to evaluate the effect of Nirgundi Ghanavati in Pureeshaja Krimi which was prepared pharmacognostically authenticated raw drugs followed by detailed analytical study as per standard protocol. The observations were systematically recorded. Presence of phytochemical components like carbohydrates, tannin, polyphenols, flavonoids support the action of the drug used for pureeshajakrimi.



Pureeshajakrimi, Nirgundi Ghanavati, Helminthiasis, Phytochemical.


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