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Research Journal of Pharmacognosy and Phytochemistry
Year : 2016, Volume : 8, Issue : 3
First page : ( 165) Last page : ( 171)
Print ISSN : 0975-2331. Online ISSN : 0975-4385.
Article DOI : 10.5958/0975-4385.2016.00028.5

Characterization of Annona muricata stem methanol extract by gas chromatography-mass spectrometry analysis

Kelechi Okoro Ebere*, James Amaku Friday, Ajah Okoro Innocent

Department of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria

*Corresponding Author E-mail: ifeanyiotuokere@gmail.com

Online published on 18 October, 2016.

Abstract

Annona muricata extract are extensively used as traditional remedy for a variety of illnesses like cancer, diabetes, hypertension and malaria. Methanol extract of Annona muricata (soursop) stem were analyzed using gas chromatography-mass spectrometry method. The result obtained from the GC-MS analysis of methanol extract of Annona muricata stem led to identification of ten (10) compounds in which 1-(4-hydroxy-6-methyl-2-pyrimidinyl)-2-aziridinone, hexadecanoic acid (palmitic acid) and 9-octadecanoic acid(oleic acid) are the major component reported with significant bioactive impact. The components were identified by comparing their retention indices and mass spectra fragmentation patterns with those stored in the National Institute of Standards and Technology (NIST) library.

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Keywords

Chromatogram, Annona muricata, retention indices, mass spectra.

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