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Research Journal of Pharmacognosy and Phytochemistry
Year : 2019, Volume : 11, Issue : 4
First page : ( 217) Last page : ( 221)
Print ISSN : 0975-2331. Online ISSN : 0975-4385.
Article DOI : 10.5958/0975-4385.2019.00037.2

Phytochemical Analysis and Pharmacological Screening of Caralluma fimfriata wall. Whole Plant Extract

Sheela S. Thorat1, Poonam J. Patil2

1Adarsh College of Pharmacy, Vita

2Assiatant Professor, Department of Pharmaceutical Chemistry, Adarsh College of Pharmacy, Vita

*Corresponding Author E-mail: ssheelathorat@gmail.com

Online published on 31 December, 2019.

Abstract

Herbal plants are natural sourcefor obtaining natural medicines. The Caralluma fimfriata wall plant belongs to family Asclepiadaceae. The plant contain different chemical constituent such as alkaloid, flavonoid The main aim of the study was to extract the plant material by using methanol as a solvent by using soxhlet extraction method. from the phytochemical analysis, the plant was showed chemical constituent. The isolation and separation of chemical constituent were done by chromatograhic technique such as thin layer chromatography and column chromatography. The each chemical constituent were identified by performing its physical and chemical test. The isolated chemical constituent were subjected to further study that is it was used for spectral analysis, by using UV-Visible spectrophotometer, IR, NMR spectroscopy, Mass spectroscopy, The methanolic extract of Caralluma fimbriata was further used for pharmacological study such as immunomodulatory activity. The increase in immunomodulatory activity of C. fimbriata was done by using neutrophil adhesion test.

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Keywords

Caralluma Fimbiata, Chromatographic analysis, Spectral analysis, Immunomodulatory activity.

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