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Research Journal of Pharmaceutical Dosage Forms and Technology
Year : 2016, Volume : 8, Issue : 3
First page : ( 218) Last page : ( 220)
Print ISSN : 0975-234X. Online ISSN : 0975-4377.
Article DOI : 10.5958/0975-4377.2016.00030.6

A Review on Solid Lipid Nanoparticle

Patil Amol M*, Todkar Rohit R, Dipak Gumte S, Mohite S.K., Magdum C.S.

Rajarambapu College of Pharmacy, Kasegaon Tal-Walwa Dist Sangli, 415 404

*Corresponding Author E-mail: amp1216@rediffmail.com

Online published on 18 October, 2016.

Abstract

Solid lipid nanoparticles (SLN) are the emerging field of nanotechnology having many potential applications in drug delivery as well as in research. Lipid nanoparticles offer possibility to develop new therapeutics due to their unique size dependent properties. The ability of incorporating drug molecules into nanocarriers provides a new prototype in drug Delivery which could be used for drug targeting. Therefore solid lipid nanoparticles have great promise for increasing the goal of controlled and site specific drug delivery. Present review focus on broad treatment of solid lipid nanoparticles with their aims, production procedures, advantages, limitations and their possible remedies. SLN are sub-micron colloidal carriers ranging from 50 to 1000 nm, which are composed of physiological lipid, dispersed in water or in aqueous surfactant solution. Solid lipid nanoparticle offer unique properties such as very small size, large surface area, high drug loading and the interaction of phases at the interface and are attractive for their potential to increase performance of pharmaceuticals.

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