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Research Journal of Pharmaceutical Dosage Forms and Technology
Year : 2020, Volume : 12, Issue : 2
First page : ( 125) Last page : ( 130)
Print ISSN : 0975-234X. Online ISSN : 0975-4377.
Article DOI : 10.5958/0975-4377.2020.00022.1

Nanoemulgel: A Process Promising in Drug Delivery System

Harshitha V.*, Swamy M. Venkata, Kumar D. Prasanna, Rani K. Sai, Trinath A.

Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak District– 502313, Telangana, India

*Corresponding Author E-mail: mvenkataswamyviper@gmail.com

Online published on 10 August, 2020.

Abstract

Nanoemulsion was described as a promising delivery system for various drugs, including biopharmaceuticals. Nanoemulsion is a heterogeneous network consisting of one immiscible liquid that was distributed within another liquid as droplets. This study aimed to investigate the nanoemulgel as a transdermal delivery system for a drug that is poorly water-soluble. Different components of nanoemulsion (oil, surfactant, and cosurfactant) were selected based on the solubility and emulsification capacity. A high-pressure Homogenization technique was used for Nanoemulsion preparation. The gelling agent was applied to transform nanoemulsion to nanoemulgel as a gel matrix. Nanoemulgels loaded with drugs were characterized for particle size, SEM, viscosity, spreadability, extrudability, pH, Stability.

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Keywords

Nano emulsion, gelling agents, nanoemulgel.

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