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Research Journal of Pharmaceutical Dosage Forms and Technology
Year : 2020, Volume : 12, Issue : 2
First page : ( 45) Last page : ( 48)
Print ISSN : 0975-234X. Online ISSN : 0975-4377.
Article DOI : 10.5958/0975-4377.2020.00007.5

Formulation and Evaluation of Herbal Anti-bacterial gel containing Ethanolic extracts of Rosa indica and Tagetes minuta

Mandadi Sandhya*, Prathyusha K., Rani M., Goud K. Sridivya, Reddy Kalivemula Divya, Swamy M. Venkata

Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak District– 502313, Telangana, India

*Corresponding Author E-mail: mvenkataswamyviper@gmail.com

Online published on 10 August, 2020.

Abstract

The present research has been undertaken with the aim to formulate and evaluate herbal gel containing ethanolic extracts of Rosa indica and Tagetes minuta. The antibacterial activity and phytochemical screening was performed for ethanolic extract. The gel preparation was designed by utilizing ethanol extract of Rosa indica and Tagetes minuta petals in varied concentrations (1.0%, 2.0%, 4.0%) and evaluated using physiological measurements. The gel was formulated by using polymer carbopol 934. Rosa indica and Tagetes minuta petals, methyl paraben, propyl paraben and required amounts of distilled water. The antibacterial activity of the gel was evaluated by agar well diffusion method by using microbial strains are E.coli and Staphylococcus aureus. The physicochemical parameters (pH, viscosity, spreadability and homogeneity) was determined. The results showed that formulation containing 4% concentration of gel containing ethanolic extracts of Rosa indica and Tagetes minuta have better antibacterial activity than other formulations.

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Keywords

Formulation, Evaluation, herbal anti-bacterial gel, ethanolic extracts.

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