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Research Journal of Pharmaceutical Dosage Forms and Technology
Year : 2019, Volume : 11, Issue : 2
First page : ( 134) Last page : ( 136)
Print ISSN : 0975-234X. Online ISSN : 0975-4377.
Article DOI : 10.5958/0975-4377.2019.00022.3

Medicinal Plants used for the Treatment of Parkinson's Disease

Nimitha V., Venkataswamy M.*, Vaishnavi P., Manisha M. Sai, Swathi V., Saritha R.

Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak District-502313, Telangana, India

*Corresponding Author E-mail: mvenkataswamyviper@gmail.com

Online published on 15 May, 2019.

Abstract

Parkinsonism is single of the regular neurodegenerative diseases, which is distinguished through a discriminating and advancement deterioration of dopaminergic neurons, root a sequence of sign which might finally persuade automatic cell demise, although the etiology of parkinsonism ruins unknown, current studies have optional that oxidative stress(OS), generate apoptosis which results in mitochondrial defects, neuroinflammation may also play important roles in its pathogenesis. Various agents as 6-Hydroxydopomine(6-OHDA), 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, Rotenone a neurotoxin commonly and many more are used in models of PD, induces selective catecholaminergic cell death, mediated by reactive oxygen species(ROS) and mitochondrial defects.

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Keywords

Parkinson's, Disease, Medicinal Plants, Rotenone.

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