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Research Journal of Pharmaceutical Dosage Forms and Technology
Year : 2018, Volume : 10, Issue : 2
First page : ( 103) Last page : ( 108)
Print ISSN : 0975-234X. Online ISSN : 0975-4377.
Article DOI : 10.5958/0975-4377.2018.00016.2

Understanding the Concept of Mucoadhesive Drug Delivery System: A Novel Approach over Conventional Dosage Forms

Kumar Umesh, Lal Khuman, Patel Navneet,  Lekhraj, Prakash Jai,  Omkar, Prakash Jai, Gurjar Rakesh, Gupta Achyutanand, Prakash Chandra, Agrawal Mukta,  Ajazuddin, Tripathi D. K., Alexander Amit*

Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, India, 490024

*Corresponding Author E-mail: itsmeamitalex@gmail.com

Online published on 7 July, 2018.

Abstract

Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention. Mucoadhesive dosage forms may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release for the improved therapeutic outcome. Application of dosage forms to mucosal surfaces may be of benefit to drug molecules not amenable to the oral route, such as those that undergo acid degradation or extensive first-pass metabolism. The mucoadhesive ability of a dosage form is dependent upon a variety of factors, including the nature of the mucosal tissue and the physicochemical properties of the polymeric formulation. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.

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Keywords

Mucoadhesion, mucoadhesive system, bioadhesion, transmucosal, transdermal, bioavailability.

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