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Pesticide Research Journal
Year : 2015, Volume : 27, Issue : 2
First page : ( 252) Last page : ( 257)
Print ISSN : 0970-6763. Online ISSN : 2249-524X.

Acute Toxicity of Acetamiprid in Rats

Mondal Samiran1,*, Ghosh RC1, Purohit Kamal2

1Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Durg, Chhattisgarh, India

2Department of Veterinary Pathology, Rajasthan University of Veterinary and Animal Sciences, Rajasthan, India

*Corresponding author E-mail: vetsamiran@gmail.com

Online published on 5 January, 2016.

Abstract

The pathology of acute acetamiprid toxicity in female wistar rats in reported. The approximate lethal dose (ALD) by oral route was found to be 506 mgkg−1 body weight. The toxicity signs were respiratory distress, hyperaesthesia, extensive tremors and terminal clonic convulsion, coma and death. At necropsy, severe haemorrhages in lungs and mild congestion in liver were noticed. Microscopically, congestion, haemorrhages and necrosis were found in liver, lungs, spleen and heart.

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Keywords

Acetamiprid, lethal dose, rat.

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