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Journal of Immunology and Immunopathology
Year : 2012, Volume : 14, Issue : 1
First page : ( 14) Last page : ( 21)
Print ISSN : 0972-0561. Online ISSN : 0973-9149.
Article DOI : 10.5958/j.0972-0561.14.1.003

Studies on Immunomodulatory Effects of Ocimum sanctum and Levamisole in Broiler Chicks Vaccinated against Newcastle Disease

Prasad B1, Prasad A1, Tiwary BK1, Ganguly S2,*

1Faculty of Veterinary Science & Animal Husbandry, Department of Veterinary Microbiology, Birsa Agricultural University, Ranchi - 834 006, Jharkhand, India

2Faculty of Fishery Sciences, Department of Fish Processing Technology, AICRP-PHT (I.C.A.R.) [Kolkata Centre], West Bengal University of Animal and Fishery Sciences, Kolkata - 700 094, West Bengal, India

*E-mail id: ganguly38@gmail.com


The present study was carried out to determine the immunogenic potential of levamisole and Ocimum sanctum in broiler chicks vaccinated against Newcastle disease, with their effect on serum protein profile like serum total protein, albumin and globulin concentrations, albumin: globulin (A:G) ratio and body weight gain. A potential effect was found in the form of increase in mean haemagglutination inhibition (HI) antibody titer, serum mean total protein, albumin and globulin concentrations and average body weight gain in levamisole- and O. sanctum-treated groups rather than the control group at different post-vaccination intervals. On the contrary, average A:G ratio was found to be higher in the control group at different post-vaccination intervals.



Immunogenic potential, Levamisole, Ocimum sanctum, Chicks.


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