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International Journal of Technology
Year : 2017, Volume : 7, Issue : 2
First page : ( 85) Last page : ( 89)
Print ISSN : 2231-3907. Online ISSN : 2231-3915.
Article DOI : 10.5958/2231-3915.2017.00014.1

Synthesis and Antimicrobial Activity of Mono, Di and Tri Substituted Aromatic Amines and Napthyl Amine Cyclic Imides Derivatives

Singh Kulveer1, Kumari Suman1, Gupta Y.K.2,*

1Research Scholar, School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), India

2Head Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India

*Corresponding Author E-mail: ykgbkbiet@rediffmail.com, ykgbkbiet@yahoo.com, ykgbkbiet123@gmail.com

Online published on 5 April, 2018.

Abstract

The cyclic imides comprising the most common heterocyclic elements like nitrogen, oxygen and sulphur assumes a fundamental part in the improvement of pharmaceutical, medicinal, chemical and agricultural fields. The cyclic imide derivatives were prepared by reacting succinic anhydride with substituted aromatic amines and napthyl amine to get 3-(N-phenyl carbamoyl) propanoic acid and 3-(Nnapthyl carbamoyl) propanoic acid. These intermediates undergo ring closer with acetyl chloride furnished five membered cyclic imides derivatives. Every one of these derivatives was screened for their antimicrobial activities.

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Keywords

Cyclic imides, Antimicrobial Activity, Heterocyclic, 3-(N-phenylcarbamoyl) propanoic acid, 3(N-napthylcarbamoyl) propanoic acid.

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