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Indian Journal of Public Health Research & Development
Year : 2018, Volume : 9, Issue : 12
First page : ( 805) Last page : ( 809)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2018.01944.7

Indirect Effect of Smoking on Liver Function: A Comparative Study among Iraqi Students in Baghdad City

Al-Fartusie Falah S.1,*, Al-Bairmani Hassanain K.1, Eltayef Emad M.1, Yousif Ahmed H2

1Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq

2Ministry of Health, Baghdad, Iraq

*Corresponding author: Falah S. Al-Fartusie. Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq; Email: sci.falah.al_fartusie@uomustansiriyah.edu.iq

Online published on 2 February, 2019.

Abstract

Smoking is a process in which a substance like tobacco is burned to produce smoke that inhales and absorbed into the bloodstream. The cigarette smoking is one of the greatest causes of illness, such as lung cancer, and premature death. The present study was constructed to evaluate the effect of cigarette smoking on the liver biochemical state. The study includes 50 smokers as patient group and 50 (age and sex matched) non-smokers as control group. The liver functions tests; aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein and alkaline phosphatase (ALP) were estimated spectrophotometrically. The results revealed that there was a signifcant reduction in the levels of AST, ALT, serum total protein and ALP of smokers in comparison with the healthy control (non-smokers) group. Also the results revealed the presence of a positive correlation between ALT and AST. To conclude, alterations in liver parameters levels could be attached to the oxidative stress created through the accumulative effect of inhaled smoke as well as the interaction of absorbed toxic chemicals like nicotine. Therefore, the association between smoking attitude and liver functions tests should be carefully analyzed.

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Keywords

Liver, smoking, ALP, ALT, AST and total protein.

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