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Indian Journal of Public Health Research & Development
Year : 2019, Volume : 10, Issue : 4
First page : ( 369) Last page : ( 373)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2019.00720.4

Evaluation of Some Biochemical Markers in Patients Serum of Myocardial Infarction and Heart Failure

Lateef Ahmed Salih1,*, Nasser Saddam Jumaa2, Mutar Ayad Abdulrazzaq1

1Department of Medical Laboratory Techniques, AL-Ma'arif University College, Ramadi, Anbar, Iraq

2Department of Pharmaceutics, College of Pharmacy, University of Anbar, Ramadi, Anbar, Iraq

*Corresponding author: Ahmed Salih Lateef, Department of Medical Laboratory Techniques/AL-Ma'arif University College, Anbar/Iraq, Email: aalkuba6@gmail.com

Online published on 6 April, 2019.

Abstract

Heart disease is a common disease in the world and lead to the mortality. The aim of this study is to evaluate the diagnostic values of serum biochemical markers such as hs-CRP, LDH and myoglobin in patients with some heart diseases such as (AMI) and (HF). Hs-CRP and myoglobin were estimated by using a sandwich immune detection method, and LDH activity by enzymatic method using semi-automated chemistry analyzer. Our data revealed that serum hs-CRP, LDH, and myoglobin levels showed a high significant differences in patient groups compared with control group, whereas comparison patient groups between them also showed high significant differences except in hs-CRP levels they were indicates no significant values. Also LDH levels showed high significant in both patient groups compared with the levels of hs-CRP and myoglobin. Finally these parameters now play significant role in the diagnosis of disease and our finding suggest that the elevated levels of hs-CRP, LDH and myoglobin are a significant predictor and considered markers for myocardial damage and necrosis.

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Keywords

Biochemical Markers, Myocardial Infarction, Heart Failure, hs-CRP, Myoglobin, LDH.

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