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Indian Journal of Forensic Medicine & Toxicology
Year : 2019, Volume : 13, Issue : 1
First page : ( 177) Last page : ( 180)
Print ISSN : 0973-9122. Online ISSN : 0973-9130.
Article DOI : 10.5958/0973-9130.2019.00036.7

Prospective Anaylysis of Electrolytic Changes in Vitreous Humour Regarding Estimation of Time Since Death

Nasim R Mohamed1, Selvaraj T2

1Assistant Professor, Forensic Medicine, Thoothukudi Medical College

2Professor & H.O.D, Forensic Medicine, Madurai Medical College

Online published on 8 February, 2019.


Estimation of time since death is a practical task daily in forensic casework. The main principle of determination of the time since death is the calculation of a measurable time which will be immensely useful for the investigation of unnatural death by the investigating police officer.

Vitreous humor is a fluid that is relatively well protected from postmortem degradation and contamination due to its postmortem stability. The biochemical constituents of vitreous humor, especially potassium have been widely used in postmortem interval examination. The time dependent rise of vitreous potassium levels in the post mortem period has been considered to be helpful in PMI determination.

Out of 100 autopsy cases in GRH Madurai when dying of natural and unnatural causes, TSD was estimated using vitreous humor electrolytes changes. A linear association was obtained upto certain hours, when mean value of k+ level plotted against PMI on a graph.



Vitreous humor, potassium, postmortem interval.


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