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Indian Journal of Contemporary Dentistry
Year : 2015, Volume : 3, Issue : 1
First page : ( 64) Last page : ( 68)
Print ISSN : 2320-5806. Online ISSN : 2320-5962.
Article DOI : 10.5958/2320-5962.2015.00015.7

Role of Matrix Metalloproteinase Inhibitors and Collagen Cross Linkers in Resin-dentin Bonding

Nagpal Rajni1, Singh Shipra2, Singh Payal2, Sharnam Tushar2, Manuja Naveen3

1Professor, Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh

2Postgraduate Student, Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh

3Professor, Department of Pediatric Dentistry, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh

Online published on 10 February, 2015.

Abstract

Mechanical, physical, and functional properties of dental adhesives have been improved as a result of numerous investigations to achieve chemical balance between their hydrophilic and hydrophobic functional components. However degradation of the adhesive-dentin interface, with time, is a major limitation of contemporary simplified adhesive systems. Bond degradation occurs via water sorption, hydrolysis of ester linkages of methacrylate resins, and activation of endogenous dentin matrix metalloproteinases. This review discusses the role of Matrix Metalloproteinase Inhibitors and Collagen Cross Linkers in preserving the resin dentin bond.

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Keywords

AdhesionMatrix metalloproteinasesCollagen cross-linkersdurability.

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