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Indian Journal of Contemporary Dentistry
Year : 2013, Volume : 1, Issue : 2
First page : ( 44) Last page : ( 48)
Print ISSN : 2320-5806. Online ISSN : 2320-5962.
Article DOI : 10.5958/j.2320-5962.1.2.030

Mucocutaneous Features of Pemphigus Vulgaris and its Management - A Case Report

Gupta Manish1,*, Devi Parvathi2, Aggarwal Avanti3

1Senior Lecturer, Department of Oral Medicine & Radiology, Sri Bankey Bihari Dental College & Hospital, Ghaziabad

2Professor & Head of Department, Department of Oral Medicine & Radiology, Rama Dental College, Hospital & Research Centre, Kanpur

3Senior Lecturer, Department of Oral Medicine & Radiology, Rajasthan Dental College, Hospital & Research Centre, Jaipur

*Corresponding author: Manish Gupta, Senior Lecturer, E-mail address: manish.omr@gmail.com, C-30 Sarita Vihar, New Delhi 110076

Online published on 9 September, 2013.

Abstract

Pemphigus vulgaris is a chronic vesicular-ampullar mucocutaneous disease that almost always produces oral manifestations. The pemphigus diseases are a group of antibody mediated disorders that manifest as blistering conditions of the skin and/or mucus membranes. This is a case report of a 40 year old female patient who presented with a six month history of oral ulceration. There were no lesions on the skin or other mucosal sites. Histology and immunostaining were consistent with Pemphigus vulgaris. Intralesional corticosteroids were instituted and marked improvement was noted. Chronic oral ulcerations can be the sole manifestation of Pemphigus vulgaris, atleast initially, that can be subsided by the use of intralesional corticosteroids. Early recognition of this lesion may prevent delayed diagnosis and inappropriate treatment of a potentially chronic dermatological condition.

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Keywords

Pemphigus, Corticosteroids, Intralesional Steroids, Systemic Steroids, Immunoflourescence, Autoantibodies.

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