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International Journal of Advances in Nursing Management
Year : 2018, Volume : 6, Issue : 2
First page : ( 93) Last page : ( 97)
Print ISSN : 2347-8632. Online ISSN : 2454-2652.
Article DOI : 10.5958/2454-2652.2018.00020.3

Valuating concentration of Cea, Ca 19-9 and some biochemical parameters in patients with colorectal cancer

Du Vu Van1,*, Lam Nguyen Duc2, Tung Dao Van3

1National Hospital of Obstetrics and Gynecology, Vietnam

2Hanoi Hospital of Obstetrics and Gynecology, Vietnam

3Haiphong University of Medicine and Pharmacy, Vietnam

*Corresponding Author E-mail: pthedong@gmail.com

Online published on 21 August, 2018.

Abstract

Colorectal cancer has a high proportion of people infected in the world and if detected early, there is a high possibility of cure. The writing focuses on valuating markers of concentrations of CEA, CA 19-9 and some biochemical parameters in patients with colorectal cancer after surgery and treatment for colorectal cancer. Cross-sectional study is implemented on 162 patients with colorectal cancer who underwent surgeries at Vietnam-Czech Friendship Hospital, Vietnam. The results show that average age of women in the study is 64, 4±10, 6 which is higher than men (56, 7±11, 1) (p<0, 05). CEA concentration before surgery is 3, 75 ng/ml which is higher than the CEA concentration after surgery for 1–3 months at 1, 93 ng/ml and after surgery for 3 to 6 months at 2, 19 ng/ml (p<0, 05). CEA concentration before surgery is 30, 96 ng/ml which is higher than the CEA concentration after surgery for 1–3 months at 23, 33 ng/ml, but being lower after surgery for 3 to 6 months at 61, 0 ng/ml (p<0, 05). The concentration of CA19-9 has changes before and after the surgery, but the difference is not statistically significant. There was no differences before and after surgery between biochemical indices such as urea, creatinine, GOT and GPT; therefore, CEA in combination with CA19-9 increases the accuracy of the diagnosis, prognosis and monitoring for the colorectal cancer.

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Keywords

CEA, CA19-9, Cancer, Colorectal, Vietnam.

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