Wagner's Granulomatosis D'Souza Molly, Sr. UMI Nives* Associate Professor, Holy Family Institute of Nursing Education, Premier Road, Kurla West, Mumbai-400070 *Corresponding Author E-mail: nivesdsouza25@gmail.com
Online published on 24 May, 2018. Abstract Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis, is a rare multisystem autoimmune disease of unknown etiology. Its hallmark features include necrotizing granulomatous inflammation and pauci-immune vasculitis in small-and medium-sized blood vessels. Granulomatosis with polyangiitis (GPA) is a serious disease and without treatment can be fatal within months. Management is directed toward stopping the inflammation process by suppressing the immune system.1 Granulomatosis with polyangiitis poses a significant diagnostic dilemma due its diverse presentations. Seemly isolated sites of disease, such as oral ulcers, may present to physicians working in primary care settings, the emergency room, and subspecialty fields as well as to dentists. Oral presentations are particularly challenging to identify and require a high index of suspicion and a detailed knowledge of the condition in order to diagnose and treat3. Top Keywords Wagner's Granulomatosis, GPA (Granulomatosis with Polyangitis), autoimmune disease, ANCA (antineutrophil cytoplasmic antibody), Scleritis. Top |