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International Journal of Advances in Nursing Management
Year : 2018, Volume : 6, Issue : 1
First page : ( 15) Last page : ( 18)
Print ISSN : 2347-8632. Online ISSN : 2454-2652.
Article DOI : 10.5958/2454-2652.2018.00004.5

Wagner's Granulomatosis

D'Souza Molly, Sr. UMI Nives*

Associate Professor, Holy Family Institute of Nursing Education, Premier Road, Kurla West, Mumbai-400070

*Corresponding Author E-mail: nivesdsouza25@gmail.com

Online published on 24 May, 2018.

Abstract

Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis, is a rare multisystem autoimmune disease of unknown etiology. Its hallmark features include necrotizing granulomatous inflammation and pauci-immune vasculitis in small-and medium-sized blood vessels. Granulomatosis with polyangiitis (GPA) is a serious disease and without treatment can be fatal within months. Management is directed toward stopping the inflammation process by suppressing the immune system.1

Granulomatosis with polyangiitis poses a significant diagnostic dilemma due its diverse presentations. Seemly isolated sites of disease, such as oral ulcers, may present to physicians working in primary care settings, the emergency room, and subspecialty fields as well as to dentists. Oral presentations are particularly challenging to identify and require a high index of suspicion and a detailed knowledge of the condition in order to diagnose and treat3.

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Keywords

Wagner's Granulomatosis, GPA (Granulomatosis with Polyangitis), autoimmune disease, ANCA (antineutrophil cytoplasmic antibody), Scleritis.

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