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Indian Journal of Applied Basic Medical Sciences
Year : 2013, Volume : 15a, Issue : 20
First page : ( 12) Last page : ( 17)
Print ISSN : 0975-8917. Online ISSN : 0000-0000.

Study of ser. follicular stimulating, lutienising & Prolactin hormonal levels in primary infertility

Turankar Sunita A1, Turankar Avinash V2

1Department of Biochemistry Grant Medical College, JJ groups of hospital, Mumbai

2Department of Pharmacology, GMC, Nagpur.

Online published on 13 February, 2013.

Abstract

Objectives

The aim of the study was to estimate the levels of follicle stimulating hormone, luteinizing hormone and prolactin hormone in Primary infertile women in Mumbai, Maharashtra, India

Methodes

The present investigation was carried out at Biochemistry Department, functioning at Grant Medical College & Sir J.J. Group of Hospitals, Byculla, Mumbai, from May 2011 to August 2011.Sample size was 30 Primary infertility Female. The inclusion criteria for the selection of cases were diagnosis of primary infertility, age between 20–40 years and duration of marriage more than one year. The exclusion criteria that were adopted during case selection were male factor infertility and amongst the female factors were tubal factor, any congenital anomaly of the urogenital tract, or any obvious organic lesion.The protocol for infertility work up in the women included: a detailed medical history, a gynecological examination, a hormonal profile (prolactin, FSH and LH). Five milliliters of fasting venous sample obtained in the morning of day second of menstrual cycle for serum biochemical analysis. Serum was separated and stored for further analysis… All the hormones, serum prolactin, LH and FSH were estimated using chemiluminiscence kits.

Conclusion

The serum FSH hormonal levels of the infertile women were lower level when compared to control groups & it was found to be statistically highly significant. The serum FSH mean & SD is 6.340 ±1.497 (P<0.0001) in the infertile group and 9.98 ±2.99 in control group. The serum LH concentration was lower level in the infertile group than in the control group. & it was found to be statistically highly significant.The LH mean & SD is 4.077 ± 2.91 (P<0.0001) in the infertile group & 7.85 ±1.24 in control group. The serum Prolactin concentration was increased in infertile group compared with control group. & it was found to be statistically highly significant.The serum Prolactin mean & SD is 25.22 ±5.744 (P<0.0001)in the infertile group & 17.89±1.82 in control group.

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