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Baba Farid University Dental Journal
Year : 2019, Volume : 9, Issue : 2
First page : ( 51) Last page : ( 55)
Print ISSN : 0976-8181. Online ISSN : 2230-7273.

A comparison of sulfiredoxin level in patients with periodontitis and healthy subjects

Parihar Anuj Singh1,*, Katoch Vartika2, Wakhle Sonal3, Sharma Sakshi4, Gupta Gaurav5, Dubey Shivam6

1Reader, Department of Periodontics, People's Dental Academy, Bhopal, Madhya Pradesh, India

2Senior Lecturer, Department of Periodontics, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India

3Reader, Department of Periodontics, Peoples College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India

4Senior Lecturer, Department of Oral Medicine and Radiology, RKDF Dental College and Research Centre, Bhopal, Madhya Pradesh, India

5Reader, Department of Public Health Dentistry, RKDF Dental College and Research Centre, Bhopal, Madhya Pradesh, India

6Senior Lecturer, Department of Oral Medicine and Radiology, RKDF Dental College and Research Centre, Bhopal, Madhya Pradesh, India

*Corresponding Author Dr. Anuj Singh Parihar, Reader, Department of Periodontics, People's Dental Academy, Bhopal, Madhya Pradesh, India

Online published on 17 February, 2020.

Abstract

Background

Periodontitis is a chronic inflammatory disease mediated by host-bacterial interactions. The present study was conducted to assess sulfiredoxin level in patients with periodontitis and healthy subjects.

Materials & Methods

The present study was conducted on 20 patients with chronic periodontitis. Equal number of sex matched control was also included. They were divided into 2 Groups, group I-healthy controls (n=20) and group II-patients with generalized chronic periodontitis (n=20). Sulfiredoxin level was analyzed by enzyme-linked immunosorbent assay.

Results

The mean gingival index in group I was 0.05 and in group II was 1.21, plaque index was 0.06 in group I and 1.32 in group II, probing depth was 1.43 in group I and 4.61 in group II, CAL in group I was 0 and in group II was 4.18 mm. The difference was significant (P< 0.05). The mean sulfiredoxin level in group I was 126.5ng/ml and in group II was 172.6 ng/ml in group II. The difference was significant (P< 0.05).

Conclusion

Authors found high level of sulfiredoxin in patients with chronic periodontitis as compared to healthy subjects. Further studies with larger sample size are required to elucidate the role of sulfiredoxin in the etiopathogenesis of periodontal diseases.

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Keywords

Periodontitis, Sulfiredoxin, Enzyme-linked immunosorbent assay.

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