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Baba Farid University Dental Journal
Year : 2019, Volume : 9, Issue : 1
First page : ( 97) Last page : ( 99)
Print ISSN : 0976-8181. Online ISSN : 2230-7273.

Melatonin in Periodontal Diseases-A Review

Parihar Anuj Singh1,*, Kalburgi Veena2, Sharma Sakshi3, Gupta Gaurav4, Chaudhary Ambika5, Nasha Amit6

1Reader, Department of Periodontics, People's College of Dental Science and Research Centre, Bhopal, Madhya Pradesh, India

2Professor & Head, Department of Periodontics, People's College Of Dental Science and Research Centre, Bhopal, Madhya Pradesh, India

3Senior Lecturer, Department of Oral Medicine, RKDF Dental College & Research Centre, Bhopal, Madhya Pradesh, India

4Senior Lecturer, Department of Public Health Dentistry, RKDF Dental College & Research Centre, Bhopal, Madhya Pradesh, India

5Senior Lecturer, Department of Public Health Dentistry, Vyas Dental College & Hospital, Jodhpur, Rajasthan, India

6Senior Lecturer, Department of Periodontics, RKDF Dental College & Research Centre, Bhopal, Madhya Pradesh, India

*Corresponding Author: Dr. Anuj Singh Parihar, Reader, Department of Periodontics, People's College of Dental Science and Research Centre, Bhopal, Madhya Pradesh, India, E-mail address: Dr.anujparihar@gmail.com

Online published on 22 August, 2019.

Abstract

Melatonin is a substance that is secreted by multiple organs in Humans. In addition to playing a role in the regulation of the circadian cycle, it is also known to have antioxidant, antiinflammatory, and antioncotic effects on human tissues. Oral cavity is an easy target for many conditions such as periodontitis, mucositis, cancers, and cytotoxicity from various drugs or biomaterials. Research on melatonin as a therapeutic agent has suggested that it is effective in treating the aforementioned pathologic conditions effectively. Furthermore, melatonin tends tofavour bone regeneration by behaving as an osteoconductive scaffold. The aim of this review is to summarize the uses and potential of melatonin in management of periodontal diseases.

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Keywords

Melatonin, inflammation, anti oxidant, oral cavity, periodontitis, bone formation.

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