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Asian Journal of Research in Pharmaceutical Science
Year : 2019, Volume : 9, Issue : 2
First page : ( 97) Last page : ( 106)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2019.00015.8

Ocular Drug Delivery System: A Novel Approach

Banu Sana1,*, Ms. Farheen Syeda Ayesha2

1Assistant Professor, Deccan School of Pharmacy, Dar-Us-Salam, Aghapura, Hyderabad-500001, Telangana, India

2Student, Deccan School of Pharmacy, Dar-Us-Salam, Aghapura, Hyderabad-500001, Telangana, India

*Corresponding Author E-mail: banusana1996@gmail.com

Online published on 3 July, 2019.

Abstract

Ocular drug delivery is one of the most challenging tasks faced by Pharmaceutical researchers. The ophthalmic preparations are available as sterile, buffered, isotonic solution. Several types of dosage forms are applied as the delivery system for the ocular delivery of drugs. The most prescribed dosage form is the eye drop solution as drops are easier to administer. Characteristics of ophthalmic preparations should be non-irritating to the ocular tissue, homogenous, relatively non-greasy, should not cause blurred vision. Prolonged drug release can be achieved using ophthalmic inserts, solid devices placed in the eye, but the inserts must then be removed when they are no longer needed. Ocuserts are the new drug delivery systems which are designed in such a way that they release the drug at predetermined and predictable rates thus eliminating the frequent administration of the drug. The systems generally include controlled, delayed and or sustained release bio-erodible implantable elements having multiple layers of different materials and/or different concentrations of materials. The elements generally include an inner layer, or core, including a therapeutic agent, and one or more outer layers made of polymeric materials.

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Keywords

Ocular Inserts, Bioerodible Implantable Elements, Homogenous, Predetermined rate.

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