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Asian Journal of Research in Pharmaceutical Science
Year : 2018, Volume : 8, Issue : 4
First page : ( 253) Last page : ( 257)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2018.00042.5

Prevalence of Sub-Clinical Hypothyroidism among Diabetes Mellitus Patients with Vascular Complications

Thokada Sai Saran*, Kandregula Harsha**, Mugada Vinodkumar

Vignan Institute Pharmaceutical Technology, Andhra University, Duvvada, Visakhapatnam

*Corresponding Author E-mail: tsaisaran11@gmail.com


Online published on 25 December, 2018.


Diabetes mellitus and thyroid dysfunction are the two most commonly seen endocrine disorders in outpatient care with reported global prevalence ranging from 2.2 to 17%. Thyroid dysfunction is a spectrum of disorders of the thyroid gland which manifests either as hyper or hypothyroidism. In this case, we notice different circulating levels of TSH. Studies have found that thyroid dysfunction is much common in diabetic population compared to non-diabetic population, diabetes and thyroid disorders have been shown to influence each other mutually because of various pathological reasons. The prevalence of hypothyroidism is also based on gender, age, and other genetical factors. Publications were identified through keyword searches of electronic databases and the internet. The databases included are Pubmed, Medline, Trip Medical Database, Embase, Cochrane Library, and Science Direct. Data extraction included Information about Study information, Interventions, Search strategy, Type of review. The extraction was carried out from the studies that were identified for inclusion. Type 2 diabetic patients with subclinical hypothyroidism are associated with an increased risk of nephropathy and cardiovascular events. The clinical importance of the biochemical abnormalities is not clear. Microvascular complications have been most commonly observed.



Subclinical hypothyroidism, diabetes mellitus, prevalence, vascular complications.


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