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Asian Journal of Research in Pharmaceutical Science
Year : 2017, Volume : 7, Issue : 3
First page : ( 149) Last page : ( 156)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2017.00024.8

Preparation and Evaluation of a Mucoadhesive Polymer from the Extract of Seeds of Annona squamosa Linn

Venkataswamy M1,*, Arul B2, Sagar A Keerthi3, Mohan S Dinesh4, Vanitha K5, Alluri Ramesh6

1Asst. Professor, Department of Pharmaceutics, Vishnu Institute of Pharmaceutical Education And Research, Vishnupur, Narsapur, Medak, Telangana, India

2Professor, Department of Pharmaceutics, Vinayaka Mission's College of pharmacy Vishnupur, Salem, Tamilnadu, India

3Asst. Professor, Department of Pharmaceutics, Vinayaka Mission's College of pharmacy, Salem, Tamilnadu, India

4Asst. Professor, Department of Pharmaceutics, Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana, India

5Assoc. Professor, Department of Pharmaceutics, Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana, India

6 Professor, Department of Pharmacology, Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana, India

*Corresponding Author E-mail: venkataswamy.m@viper.ac.in

Online published on 17 October, 2017.

Abstract

Mucoadhesive drug delivery systems exploit the attraction between the mucus and polymeric drug carriers. They provide localization of the carriers within the specific body site and prolonged residence time of delivery devices. In this present work an attempt was made to isolate a mucoadhesive polymer from an indigenous plant Annona squamosa Linn and characterize its mucoadhesive properties. The results of the present investigation revealed that the prepared polymer characterized as a mucoadhesive polymer as compared with the available polymers. It shows best results in evaluation processes by shear stress, tensile strength, shear strength, falling sphere, swelling factor, viscosity, stability studies.

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Keywords

Preparation of a mucoadhesive polymer, Preparation of a mucoadhesive polymer from the extract of seeds, Annona squamosa linn, Seeds of Annona squamosa linn, Polymer from the extract of seeds of annona squamosa linn, Extract of seeds of Annona squamosa linn, Mucoadhesive polymer, Mucoadhesive polymer from the extract.

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