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Asian Journal of Research in Pharmaceutical Science
Year : 2017, Volume : 7, Issue : 3
First page : ( 141) Last page : ( 148)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2017.00023.6

Preparation and In Vitro Charactersation of Fast Disintigrating Tablets of Cimetidine

Vageesh N.M.1,*, Rafian D1, Govindamma U.1, Sura Ramya Sri2

1St. Johns College of Pharmaceutical Sciences, Yerakota, Yemmiganur, Kurnool (Dist), Andhra Pradesh

2Department of Pharmaceutics, OU Ph. D Scholar, Osmania University, Hyderabad

*Corresponding Author E-mail: vageeshpharma@gmail.com

Online published on 17 October, 2017.

Abstract

The present study was carried out to develop Fast Disintegration Tablets of Cimetidine. Kollidon, Vivasol, Tulsion 330 powder were used as Super Disintegrants. The blend of all the formulations showed good flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. Among all the formulations F7 formulation showed maximum % drug release i.e., 98.62% in 60 min hence it is considered as optimized formulation.

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Keywords

Cimetidine, Kollidon, Vivasol, Tulsion 330 and Fast Disintegration tablets.

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