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Asian Journal of Research in Pharmaceutical Science
Year : 2017, Volume : 7, Issue : 2
First page : ( 120) Last page : ( 122)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2017.00019.4

In vitro Evaluation of Antioxidant Potential of N-Acetyl-D-Glucosamine.

Potbhare Mrunali1,*, Phendarkar Nikhita2, Khobragade Deepak

1Shri Indu Institute of Pharmacy, Hyderabad

2Vijaya College of Pharmacy, Hayathnagar, Hyderabad

*Corresponding Author E-mail:

Online published on 18 September, 2017.

Abstract

Oxidative stress is an important risk factor in the pathogenesis of numerous chronic diseases. An antioxidant can be broadly defined as any substance that delays or inhibits oxidative damage to a target molecule. They mainly act by preventing damage caused to the body by free radicals. Antioxidants are very important in treating many disorders or are used as supportive treatment for various disorders. N-Acetyl-D-Glucosamine it is widely used in osteo-arthritis and many related conditions. One of the reason for its effective ness in these conditions may be its antioxidant potential. The antioxidant potential of N-Acetyl-D-Glucosamine was evaluated in vitroin the present study. DPPH scavenging activity and Hydrogen peroxide scavenging activity was used to access the antioxidant activity of N-Acetyl-D-Glucosamine. Ascorbic acid was used as standard antioxidant agent for comparing the antioxidant activity of N-Acetyl-D-Glucosamine. The results show that N-Acetyl-D-Glucosamine shows significant antioxidant activity, more than 80% as that of ascorbic acid in both the in vitro tests used in this study.

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Keywords

Antioxidant, Free radicals, Oxidative stress, N-Acetyl-D-Glucosamine, Ascorbic acid, DPPH, Hydrogen Peroxide.

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