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Asian Journal of Research in Pharmaceutical Science
Year : 2017, Volume : 7, Issue : 2
First page : ( 112) Last page : ( 114)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2017.00017.0

Anti microbial and antioxidant evolution of aqueous extract of Terminalia chebula using disc diffusion, H2O2 scavenging methods

Naidu N.*, Kumar G. Sudheer, Sivakrishna K., Anjinaik K., Kumar L. Praveen, Sneha G.

Department of Pharmacology, Bellamkonda Institute of Technology and Sciences, Podili

*Corresponding Author E-mail: narapusetty.naidu@gmail.com

Online published on 18 September, 2017.

Abstract

The biological evolution of Terminalia chebula leaves extract, plant belongs to family Combretaceae. The aqueous extract of the plant material was tested for Antimicrobial activity of against Gram positive and Gram negative bacterial strains by observing the zone of inhibition. Antimicrobial activity was done by disc diffusion method at a concentration of, 100, 250, 500 μg/disc of the extract, using ofloxacin (5μg/disc) as the standard. The bacterial strains used in the study were Staphycococcus aureus, Bacillus subtilis, Escherichia coli, Proteus vulgaris, the anti oxidant activity of by using at concentration of 5, 10, 15, 20, 25, 30 μg/ml, using Ascorbic acid as standard. The outcomes of the present study indicated that the aqueous extract of the Terminalia chebula shows the significance anti bacterial and anti oxidant activity in a concentration of 500 μg/ml, 30μg/ml respectively.

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Keywords

Terminalia chebula, aqueous extract Antibacterial activity, antioxidant activity, H2O2 scavenging method.

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