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Asian Journal of Research in Pharmaceutical Science
Year : 2016, Volume : 6, Issue : 3
First page : ( 153) Last page : ( 160)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2016.00021.7

Fast Dissolving Sublingual Film

Sangale Vaishali D.1,*, Aher Smita S.2, Saudagar Ravindra B.2

1Department of Quality Assurance Technique, KCT'S RGS College of Pharmacy, Anjaneri, Nashik, 422 213, Maharashtra, India

2Department of Pharmaceutical Chemistry, KCT'S RGS College of Pharmacy, Anjaneri, Nashik, 422 213, Maharashtra, India

*Corresponding Author E-mail: vaishalisangale90@gmail.com

Online published on 18 October, 2016.

Abstract

Orally fast dissolving films are an emerging technology with fast onset of activity and improved patient compliance. It enhances the viability of API's and gives better medication use. These formulations are suitable for cold, allergy rhinitis, asthma attacks, CNS issue where fast onset of activity is needed for quicker help. The sublingual course of medication organization is extremely compelling following the medication retained through the sublingual veins by passes hepatic first pass metabolic procedure and also gives a better bioavailability. The present article outlines the definition viewpoints, manufacturing methods like solvent casting method, evaluation parameters and applications of fast dissolving films by sublingual route It has been estimated that approximately 84% of all sales of the top selling commercially available products are delivered via the oral route. Thin film drug delivery has come forward as an advanced alternative to the traditional tablets, capsules and liquids frequently associated with prescription and OTC medications. Similar in size, shape, and thickness to a postage stamp, thin film strips are classically designed for oral administration, with the user placing the strip on or under the tongue(sublingual)or along the inside of the cheeks(buccal). These drug delivery options allows the medication to bypass the first pass metabolism thereby making the medication further available. As the strip dissolves, the drug can enter the blood stream enterically, buccally or sublingually. The permeation is superior with sublingual than buccal than palatal region.

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Keywords

Fast dissolving drug delivery, oral strips, sublingual film, Mouth dissolve.

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