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Asian Journal of Research in Pharmaceutical Science
Year : 2020, Volume : 10, Issue : 3
First page : ( 141) Last page : ( 144)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2020.00026.0

Evaluation of antiurolithiatic activity of moringa leaves by uv spectroscopic method

Banik Kabita1,*, Akshitha S.2, Poojitha O. V.2, Thulasi Ch.2, Vineetha V.2

1Assistant Professor, Bharat Institute of Technology, Mangalpally, Hyderabad, Telangana, India

2B Pharmacy, Research Scholar, Bharat Institute of Technology, Hyderabad

*Corresponding Author E-mail: banikkabita64@gmail.com

Online published on 16 September, 2020.

Abstract

The effect of M.olifera leaf against Calcium oxalate was tested by uv Spectrscopy method. calcium oxalate crystals were confirmed by UV analysis. Then the sample was treated against leaf extract and again UV analysis was done to confirm presence or absence of crystals. Two type of assay the done to confirming the property Aggression assay and nucleation assay. calcium Oxalate, Phosphate, uric acid and proteins are important markers as well as citrate and magnesium are inhibitors which were tested for the confirmation of the stone. LDH and oxalate are the enzymes of liver and kidneys are having an important role in Urolithiasis were also estimated. After studding the absorbance and turbidity of calcium oxalate solution we concluded the results, studies showed significant data to confirm the efficacy of M.olifera leaf having anti-urolithic activity. The results of present study suggest usefulness of M.olifera in the treatment of kidney stone disease.

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Keywords

M. olifera leaf, Calcium oxalate, Urolithiasis, Nucleation assay, Aggregation assay, Crystallization inhibition rate.

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