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Asian Journal of Research in Pharmaceutical Science
Year : 2020, Volume : 10, Issue : 2
First page : ( 109) Last page : ( 114)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2020.00021.1

A Review on Transdermal Drug Delivery Systems

Nagadev Ch.*, Rao M. Durga Srinivasa, Venkatesh P., Hepcykalarani D., Prema R.

Jagan's Institute of Pharmaceutical Sciences, Jangalakandrika (V)-524326, Muthukur (M), Nellore (Dist.), Andhra Pradesh, India

*Corresponding Author E-mail: nagadevchpharma@gmail.com

Online published on 3 June, 2020.

Abstract

Transdermal drug delivery systems (TDDS) are the dosage form of adhesive patch that is placed on the skin to deliver specific dose of medication through the skin and in to the blood stream. For the delivery of therapeutic agents through the human skin for systemic effects, the comprehensive morphological, bio physical and physicochemical properties of the skin are to be considered. An advantage of trans dermal drug delivery route over other type of medication is that a patch provides not only a controlled release, but also a constant administration of the drug and eliminates pulsed entry into the systemic circulation which often causes un desirable side effects. One of the most important novel drug delivery system is transdermal patch and it is a painless technique for administration of drug. The TDDS review article provides variable information regarding TDDS and its evaluation process details as a ready reference for a research scientist who is involved in TDDS.

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Keywords

Transdermal drug delivery systems, diffusion, polymer matrix, permeation enhancers, epidermis, topical, reservoir.

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