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Asian Journal of Research in Pharmaceutical Science
Year : 2020, Volume : 10, Issue : 1
First page : ( 11) Last page : ( 16)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2020.00003.X

Effect of Ethanolic root extract of Aporosa lindleyana on hepatic and renal marker enzymic status of INH-RIF induced toxicity on male albino wistar Rats.

Ramakrishnan S.1, Venkataraman R2

1Department of Biotechnology, Sri Paramakalyani College, Alwarkurichi, 627 412

2PG and Research Department of Chemistry, Sri Paramakalyani College, Alwarkurichi, 627 412

Online published on 3 June, 2020.

Abstract

In this present study focussed to explore the hepato and renal protective effect of Ethanolic Root Extract of Aporosa lindleyana (EREAL) on INH-RIF induced toxicity on rats. EREAL showed remarkable decrease on the activities of hepatic marker enzymes (AST, ALT, ALP and GGTP) and renal function markers (Urea, Uric acid and Creatinine) on the serum of INH-RIF induced rats. Near normalization of these parameters by EREAL treatment represents its ability to maintain the normal functional status of liver and kidney in INH-RIF toxicity induced rats.

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Keywords

EREAL, INH-RIF, AST, ALT, Urea, Creatinine.

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