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Asian Journal of Research in Chemistry
Year : 2015, Volume : 8, Issue : 8
First page : ( 530) Last page : ( 534)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2015.00084.X

Synthesis and Antibacterial Studies of Schiff bases derived from o-phthalaldehyde

Guguloth Hanmanthu1, Nerella Srinivas2, Kankala Shravankumar1,*, Vadde Ravinder1

1Department of Chemistry, Kakatiya University, Warangal, India-506 009

2Department of Chemistry, Govt. Degree College, Jammikunta, Karimnagar, India

*Corresponding Author E-mail: shravankankala@yahoo.com

Online published on 17 October, 2015.


A series of twelve new azomethine derivatives were synthesized by the condensation of o-phthalaldehyde with primary amine derivatives. The chemical structures of these compounds were confirmed by IR, 1H, 13C NMR, Mass and elemental analysis. Antibacterial activities of these compounds have been tested against four strains of bacteria (Bacillus subtillus, Staphylococcus aureus, Escherichia coli and Klebsiella pneumonia) and found to possess potential antibacterial activity.



o-phthalaldehyde, primary amine, schiff base, antibacterial activity.


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