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Asian Journal of Research in Chemistry
Year : 2015, Volume : 8, Issue : 3
First page : ( 195) Last page : ( 200)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2015.00035.8

Study of Synthesis and Analgesic Activity of some Benzopyrone Derivatives

Som Sukhen1,*, Jayaveera K.N.2

1Department of Pharmaceutical Chemistry, M.M.U College of Pharmacy, K.K. Doddi, Ramanagara-562159, Karnataka

2Department of Chemistry, Jawaharlal Nehru Technological University Anantapur, Ananthapuramu-515002, Andhra Pradesh

*Corresponding Author E-mail: sukhen18@rediffmail.com

Online published on 2 May, 2015.

Abstract

Benzopyrone derivatives are associated with different pharmacological activities like analgesic, anti-inflammatory, anticancer, antihepatotoxic, antibacterial, antiviral etc. Considering the potential of this particular lead molecule, different derivatives of benzopyrone condensed with amines were synthesized and evaluated for their analgesic activity. The structures of the synthesized compounds were confirmed by their analytical as well as spectral data. Some of the compounds synthesized i.e. 4a, 4c, 4e and 4g showed significant analgesic activity.

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Keywords

Analgesic activity, Amines, Tail flick method.

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