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Asian Journal of Research in Chemistry
Year : 2015, Volume : 8, Issue : 3
First page : ( 175) Last page : ( 178)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2015.00031.0

Studies on Synthesis, Characterization and Biological Activity of Salicylic acid Containing Mixed Ligand Complexes of Zn(II)ion

Md. Islam Zakirul1,  Shejutyaktar1, Md.  Shiraj-U-Ddaula1, Md. Haque Masuqul1, Md. Hossen Faruk1, Md. Farooque Akhter1, Md.  Kudrat-E-Zahan2,*

1Inorganic Research Laboratory, Department of Chemistry, University of Rajshahi, Rajshahi-6205, Bangladesh

2Dept. of Chemistry, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh

*Corresponding Author E-mail: kudrat.chem@ru.ac.bd

Online published on 2 May, 2015.

Abstract

The flexibility of zinc coordination, which allows different coordination modes and fast ligand exchange, has been suggested to be one key catalytic feature of the zinc ion which makes it an invaluable metal in biological catalysis. Mixed ligand Complexes of the Schiff base Zn(II) metals sources have been synthesized and characterized using FTIR, UV-visible spectra, metal estimation, TLC and magnetic moments measurements. Antimicrobial activity of the prepared complexes were measured as resistance to antimicrobial agents is emerging in a wide variety of nosocomial and community-acquired pathogens. The results of the study infers though zinc and salicylic acid individually demonstrated potential biological activities, however, when they were in the form of complex the biological activities were found inferior.

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Keywords

Transition metal complex, spectra, Antimicrobial activity, Zn(II), Salicylic acid.

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