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Asian Journal of Research In Chemistry
Year : 2012, Volume : 5, Issue : 6
First page : ( 791) Last page : ( 793)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.

In vitro Antibacterial Efficacy of Selected Plant Extracts, Streptomycin and their Combination

Abhipsa V., Manasa M., Poornima G., Rekha C., Kekuda T.R. Prashith*

Department of Microbiology, SRNMN College of Applied Sciences, NES Campus, Balraj Urs Road, Shivamogga-577201, Karnataka, India

*Corresponding Author E-mail: p.kekuda@gmail.com

Online published on 7 February, 2013.

Abstract

The present study was undertaken to determine antibacterial potential of combination of methanol extract of five plants namely Polyalthia longifolia, Vitex negundo, Tephrosia purpurea, Jasminum arborescens and Abrus pulchellus and an aminoglycoside antibiotic Streptomycin against bacteria. The antibacterial activity of extracts, Streptomycin and their combination was determined against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa by Agar well diffusion method. Extracts, antibiotic and their combination resulted in marked suppression of growth of Gram positive bacteria than Gram negative bacteria. Combining extracts with antibiotic showed higher inhibition of test bacteria when compared to inhibition caused by antibiotic alone. The combined effect resulting from the association of antibiotic with plant extracts against bacteria, as observed in this study, possibly leads to the development of new strategy for the treatment of infectious diseases.

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Keywords

Antibacterial activity, Soxhlet, Agar well diffusion, Antibiotic, Plant extracts.

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