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Asian Journal of Research in Chemistry
Year : 2020, Volume : 13, Issue : 4
First page : ( 283) Last page : ( 286)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2020.00055.3

Thiazolidine, a versatile ring in the treatment of various diseases: A systematic review

Bajpai Pawan, Jain Shelesh, Choubey Ankur*

School of Pharmacy, Madhyanchal Professional University, Bhopal-462024

*Corresponding Author E-mail: chaubey.ankur03@gmail.com

Online published on 16 September, 2020.

Abstract

Thiazolidine is become an important ring in the development various antagonist against different diseases such as diabetes, cancer, inflammation, microbial infection etc. Thiazolidine derivatives showed improved pharmacological activity in different pathophysiological conditions than its standard drug. Thiazolidine 2,4-dione, 1, 3 thiazolidines, 2, 4 dione,4-oxo thiazolidine contains basic thiazolidine skeleton. The present science migrates to the development of drugs on the basis of structure-based drug design in the presence of protein structure. The difference between the designed drug and their synthesis can be minimized by showing the ligand protein interaction. The present study includes the thiazolidine derivatives and their pharmacological activities in the treatment of various diseases.

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Keywords

Thiazolidine, Antibacterial, Anticancer, Anti-inflammatory.

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