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Asian Journal of Research in Chemistry
Year : 2018, Volume : 11, Issue : 3
First page : ( 649) Last page : ( 651)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2018.00116.5

Environmentally benign synthesis and biological activity of benzo[d] Thiazol-2-yl) Phenyl)-N-(5-aryl-1H-1, 2, 3-Triazol-1-yl) methanamines

Yadaiah S1, Balaraju V2, Merugu Ramchander1, Jyothi M.1,*, Eppakayala Laxminarayana2

1Mahatma Gandhi University, Anneparthy, Nalgonda-508 254 (Telangana) India

2Sreenidhi Institute of Science and Technology (Autonomous), Ghatkesar, Hyderabad-501 301 (Telangana) India

*Corresponding Author E-mail: mandalajyothi@yahoo.co.in

Online published on 21 August, 2018.

Abstract

In this present communication we report synthesis of Benzo[d]thiazol-2-yl) phenyl)-N-(5-aryl-1H-1, 2, 3-triazol1-yl)methanamines by microwave irradiation in good yields and less reaction time. All title compounds were characterized by IR, NMR and Mass spectral analyses. The antibacterial activity of the compounds was also investigated. Highest activity was seen against Staph.aureus followed by Bacillus subtilis.

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Keywords

Synthesis, methanamines, microwave assisted, antibacterial activity.

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