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Asian Journal of Research in Chemistry
Year : 2017, Volume : 10, Issue : 6
First page : ( 745) Last page : ( 749)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2017.00126.2

One Pot, Four-Component for the Synthesis of Pyrano Pyrazole Derivatives using TBAHS as Green Catalyst and their Biological Evaluation

Bhosale Vijay N.1,*, Khansole Gopinath S.2, Angulwar Jaman A.3, Choudhare Sunil S.1, Karad Ashok R.1, Wadwale Navanand B.1

1P.G. Research Centre, Department of Chemistry, Yeshwant Mahavidyalaya, Nanded (M.S.) India

2Department of Chemistry, D.A.B.N. Arts & Science College, Chikhali, Sangli (M.S.) India

3Department of Chemistry, Dayanand Science College, Latur (M.S.) India

*Corresponding Author E-mail: vijaynbhosale77@gmail.com

Online published on 26 March, 2018.

Abstract

A green, efficient and simple procedure has been developed for the synthesis of Pyrano [2, 3-c] Pyrazoles from a one pot four component condensation of ethylacetoacetate, malononitrile, hydrazine hydrate and different substituted aromatic aldehydes using Tetrabutyl ammonium hydrogen sulphate (TBAHS) as green catalyst in

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Keywords

Pyrano pyrazoles, MCRs, TBAHS, Antioxidant activity.

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