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Asian Journal of Research in Chemistry
Year : 2017, Volume : 10, Issue : 4
First page : ( 417) Last page : ( 430)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2017.00070.0

A Review on Hydrazone, the fascinating field of investigation in medicinal chemistry

Rohane Sachin H.*, Dr. Makwana Ashlesha G.

Department of Chemistry, K.B. Institute of Pharmaceutical Education and Research, Gandhinagar, 382023, India

*Corresponding Author E-mail: sachinrohane29@gmail.com

Online published on 17 October, 2017.

Abstract

Antibiotic resistance is a global public health threat. There has been considerable interest in the development of novel compounds with antimicrobial, anti-mycobacterial, and antiviral activities etc. keeping Hydrazones as a centre attraction this review has been carried forward. Hydrazone possessing an azometine-NHN=CH-proton constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new hydrazones that possess varied biological activities. Hopefully, this will allow the development of innovative new strategies for the development of novel compounds with different scheme, methods and materials.

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Keywords

Antibiotic resistance, Hydrazone, azometine, innovative strategies, broad spectrum.

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