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Asian Journal of Research in Chemistry
Year : 2017, Volume : 10, Issue : 2
First page : ( 154) Last page : ( 157)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2017.00026.8

Synthesis of 1, 3, 4-Oxadiazole

Farooqui Maqdoom*, Nazimuddin Syed

P.G. and Research Centre, Maulana Azad College of Arts, Science and Commerce, Aurangabad

*Corresponding Author E-mail: maqdoomf@gmail.com

Online published on 17 July, 2017.


Synthesis of 1, 3, 4-oxadiazole by the reaction of 2-propyl Benzo imidiazol-2-yl carbohydrazide and 1, 3, dihydro iso indo-2-yl acetic acid (Phthalyl Amino Acids) in presence of HCl and phosphoryl chloride. All the newly synthesized compounds were screened antibacterial activity which shows moderate to mild activity, and yield of the synthesized compounds were found to be 62–68%.



Oxadiazole, Carbohydrazide, Antibacterial Activity, Antifungal Activity, Phthalyl Amino Acids.


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